Global Organ-on-Chip Market Forecast 2025-2030: Growth at 40% CAGR Expected

 Global Organ-on-Chip Market Overview: 2025-2030

Base Year: 2024

Historical Years:  2020-23

Forecast Years: 2025-2030

The Global Organ-on-Chip Market size was valued at around USD 126 million in 2024 and is projected to reach USD 950 million by 2030. Along with this, the market is estimated to grow at a CAGR of around 40% during the forecast period (2025-30). 

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Global Organ-on-Chip Market Dynamics: 2025-2030

Global Organ-on-Chip Market Driver:

Growing Demand for Alternatives to Animal Testing in Drug Discovery – The worldwide market for organ-on-chip technology is driven by the growing need for alternatives to animal testing in drug discovery. To enhance safety & efficacy evaluations and lessen the ethical issues surrounding animal testing regulatory organizations like the FDA and EMA promote the use of sophisticated in-vitro models. The FDA Modernization Act 2.0. passed by the USA government in the year 2022, will greatly decrease the use of animal drug testing by promoting the use of substitute techniques like organ-on-chips. Precise simulation of human organ function through systems such as the liver and lung on chips offers increased predictive accuracy of drug toxicity and metabolism studies. For instance; Emulate's liver on a chip has been widely utilized to predict hepatotoxicity in candidates for drugs reducing dependence on animal models. This shows how Organ-On-Chip technology is changing the scenario of preclinical testing to provide ethical and cost-effective solutions for the pharmaceutical industry with alternatives to animal testing.

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Global Organ-on-Chip Market (2025-30): Segmentation Outlook

The market report has segmented the market into the following categories:

By Model Type

-Organ-Based Model- Market Size & Forecast 2020-2030, USD Million

-Disease-Based Model- Market Size & Forecast 2020-2030, USD Million

-By Material

-Polydimethylsiloxane (PDMS)- Market Size & Forecast 2020-2030, USD Million

-Polymer- Market Size & Forecast 2020-2030, USD Million

-Glass- Market Size & Forecast 2020-2030, USD Million

By Solution

-Products- Market Size & Forecast 2020-2030, USD Million

-Instruments- Market Size & Forecast 2020-2030, USD Million

-Consumables & Accessories - Market Size & Forecast 2020-2030, USD Million

-Software- Market Size & Forecast 2020-2030, USD Million

-Services- Market Size & Forecast 2020-2030, USD Million

-Custom Services- Market Size & Forecast 2020-2030, USD Million

-Standard Services- Market Size & Forecast 2020-2030, USD Million

By Organ Type

-Liver-Market Size & Forecast 2020-2030, USD Million

-Intestine-Market Size & Forecast 2020-2030, USD Million

-Kidney-Market Size & Forecast 2020-2030, USD Million

-Lung-Market Size & Forecast 2020-2030, USD Million

-Heart-Market Size & Forecast 2020-2030, USD Million

-Other organs

Based on organ type, the Liver segment leads the global market. It holds approx. 30% of the total market value. 

By Application

-Toxicology Research-Market Size & Forecast 2020-2030, USD Million

-Drug Discovery-Market Size & Forecast 2020-2030, USD Million

-Physiological Model Development-Market Size & Forecast 2020-2030, USD Million

-Stem cell Research-Market Size & Forecast 2020-2030, USD Million

-Tissue regeneration and regenerative Medicines-Market Size & Forecast 2020-2030, USD Million

-Others

By End User

-Pharmaceutical and Biotechnology Companies-Market Size & Forecast 2020-2030, USD Million

-Cosmetics Industry-Market Size & Forecast 2020-2030, USD Million

-Academic and Research Institutes-Market Size & Forecast 2020-2030, USD Million

-Others

By Region

-North America

-South America

-Europe

-The Middle East & Africa

-Asia-Pacific.

Out of them, North America dominates the Global Organ-on-Chip Market. It holds approx. 52% market share. 

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Top Companies Operating in the Global Organ-on-Chip Market:

Altis Biosystems, AlveoliX AG, Axosim, Bi/ond Solutions B.V, Cherry Biotech, CN-Bio, Emulate, Inc., Hesperos, Inc., Insphero, MesoBioTech, Mimetas B.V., Nortis Inc., React4Life, TARA Biosystems (Valo Health), TissUse GmbH and Others.

Industry Recent Development:

  • April 2024: CN Bio secured USD 21 million in Series B funding from Bayland Capital and CN Innovations Holdings Ltd. to expand its product development & scaling, meeting the rising demand for organ on a chip solution and driven by improved drug R&D efficiency and legislative changes like the US FDA Modernization Act 2.0.
  • March 2024: MIMETAS joined the Centre for Animal-Free Biomedical Translation (CPBT), which received USD134.78 million from the Dutch National Growth Fund to advance animal-free biomedical innovations.

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